개열 및 폴리아데닐화 특이성 인자 서브유닛 7은 CPSF7 [5] [6] 단백질 이다.
기능. CFIm59로도 알려진 CPSF7은 유전자 전사에 사용 되는 새롭게 합성된 프리메신저 RNA (mRNA) 분자의 3' 미번역 영역에 있는 두 개의 밀접하게 연관된 단백질 복합체의 분열 인자 이다. [7] 3개의 Cleavage and Polyadenylation Specificity Factor(CPSF) 중 하나이며, 나머지 2개 는 CFIm25(또는 CPSF5/NUDT21) 와 CFIm68(또는 CPSF6)입니다.
레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000149532 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000034820 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (December 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proceedings of the National Academy of Sciences of the United States of America . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . ^ "Entrez Gene: FLJ12529 pre-mRNA cleavage factor I, 59 kDa subunit" .^ Hardy JG, Norbury CJ (August 2016). "Cleavage factor Im (CFIm) as a regulator of alternative polyadenylation" . Biochemical Society Transactions . 44 (4): 1051–7. doi :10.1042/BST20160078 . PMID 27528751 .
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