LSM10

LSM10
식별자
에일리어스	LSM10, MST074, MSTP074, U7 소형핵 RNA 관련
외부 ID	OMIM: 617909 MGI: 2151045 HomoloGene: 13154 GeneCard: LSM10
유전자 위치(인간)
크르.	1번 염색체(인간)
끝.	36,397,908 bp
유전자 위치(마우스)
크르.	4번 염색체(쥐)
끝.	125,992,377 bp
RNA발현패턴
	상단 표시 위치:
	위근; ; 단구; ; 골격근 조직; ; 정강이뼈전근; ; 대퇴 사두근; ; 삼각근; ; 외측 광대근; ; 좌심실; ; 전전두피질; ; 상완 이두근;
	추가 참조 표현식 데이터
	없음
유전자 존재론
분자 함수	U7 snRNA 바인딩; GO:0001948, GO:0016582 단백질 결합; 히스톤프리mRNADCP결합; RNA결합;
셀룰러 컴포넌트	카잘체; U7 snRNP; 핵; 핵소체; 핵체;
생물학적 과정	유사분열세포주기의 G1/S 전이 양성조절; RNA중합효소II 전사종료; mRNA 처리; 히스톤mRNA대사과정; RNA 스플라이싱;
	출처:아미고 / QuickGO
맞춤법
	84967
	116748
	ENSG00000181817
	ENSMUSG000050188
	Q969L4
	Q8QZX5
	NM_032881
	NM_001163266; NM_138721
	NP_116270
	NP_001156738; NP_620046
	위키데이터
인간 보기/편집	마우스 표시/편집

U7 snRNA 관련 Sm 유사 단백질 LSm10은 LSM10 ^[5]^[6]유전자에 의해 인체 내에서 암호화되는 단백질이다.

상호 작용

LSM10은 LSM3와 ^[7]^[8]상호작용하는 것으로 나타났습니다.

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U7 소핵 RNA

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000181817 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리즈 89: ENSMUSG000050188 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Pillai RS, Will CL, Lührmann R, Schümperli D, Müller B (Oct 2001). "Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein" (PDF). The EMBO Journal. 20 (19): 5470–9. doi:10.1093/emboj/20.19.5470. PMC 125645. PMID 11574479.
^ "Entrez Gene: LSM10 LSM10, U7 small nuclear RNA associated".
^ Lehner B, Sanderson CM (Jul 2004). "A protein interaction framework for human mRNA degradation". Genome Research. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

추가 정보

Dominski Z, Zheng LX, Sanchez R, Marzluff WF (May 1999). "Stem-loop binding protein facilitates 3'-end formation by stabilizing U7 snRNP binding to histone pre-mRNA". Molecular and Cellular Biology. 19 (5): 3561–70. doi:10.1128/mcb.19.5.3561. PMC 84148. PMID 10207079.
Dominski Z, Erkmann JA, Yang X, Sànchez R, Marzluff WF (Jan 2002). "A novel zinc finger protein is associated with U7 snRNP and interacts with the stem-loop binding protein in the histone pre-mRNP to stimulate 3'-end processing". Genes & Development. 16 (1): 58–71. doi:10.1101/gad.932302. PMC 155312. PMID 11782445.
Pillai RS, Grimmler M, Meister G, Will CL, Lührmann R, Fischer U, Schümperli D (Sep 2003). "Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing". Genes & Development. 17 (18): 2321–33. doi:10.1101/gad.274403. PMC 196468. PMID 12975319.
Hassel S, Eichner A, Yakymovych M, Hellman U, Knaus P, Souchelnytskyi S (May 2004). "Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry". Proteomics. 4 (5): 1346–58. doi:10.1002/pmic.200300770. PMID 15188402. S2CID 6773754.
Lehner B, Sanderson CM (Jul 2004). "A protein interaction framework for human mRNA degradation". Genome Research. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
Azzouz TN, Pillai RS, Däpp C, Chari A, Meister G, Kambach C, Fischer U, Schümperli D (Oct 2005). "Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes". The Journal of Biological Chemistry. 280 (41): 34435–40. doi:10.1074/jbc.M505077200. PMID 16087681.
Wagner EJ, Marzluff WF (Sep 2006). "ZFP100, a component of the active U7 snRNP limiting for histone pre-mRNA processing, is required for entry into S phase". Molecular and Cellular Biology. 26 (17): 6702–12. doi:10.1128/MCB.00391-06. PMC 1592837. PMID 16914750.

인간 염색체 1번 유전자에 대한 이 기사는 뭉툭한 것이다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG00000181817 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리즈 89: ENSMUSG000050188 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11574479-5] Pillai RS, Will CL, Lührmann R, Schümperli D, Müller B (Oct 2001). "Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein" (PDF). The EMBO Journal. 20 (19): 5470–9. doi:10.1093/emboj/20.19.5470. PMC 125645. PMID 11574479.

[entrez-6] "Entrez Gene: LSM10 LSM10, U7 small nuclear RNA associated".

[pmid15231747-7] Lehner B, Sanderson CM (Jul 2004). "A protein interaction framework for human mRNA degradation". Genome Research. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.

[pmid16189514-8] Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

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LSM10

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