프리폴딘 서브유닛4 는 PFDN4 [5] [6] [7] 유전자 에 의해 인체 내에서 코드되는 단백질 이다.
기능. 이 유전자는 프리폴딘 베타 서브유닛의 일원을 암호화한다. 코드화된 단백질은 새롭게 합성 된 폴리펩타이드를 결합하고 안정시키는 분자 샤페론 복합체 인 프리폴딘의 6개 서브유닛 중 하나입니다. 2개의 알파 서브유닛과 4개의 베타 서브유닛으로 구성된 복합체는 6개의 돌출 코일 [7] 코일 이 있는 이중 베타 배럴 어셈블리를 형성합니다.
레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000101132 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000052033 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Vainberg IE, Lewis SA, Rommelaere H, Ampe C, Vandekerckhove J, Klein HL, Cowan NJ (May 1998). "Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin" . Cell . 93 (5): 863–73. doi :10.1016/s0092-8674(00)81446-4 PMID 9630229 . S2CID 16011829 . ^ Iijima M, Kano Y, Nohno T, Namba M (Apr 1996). "Cloning of cDNA with possible transcription factor activity at the G1-S phase transition in human fibroblast cell lines". Acta Medica Okayama . 50 (2): 73–7. PMID 8744932 . ^ a b Coraboeuf E, Deroubaix E, Hoerter J (May 1976). "Control of ionic permeabilities in normal and ischemic heart" . Circulation Research . 38 (5 Suppl 1): I92–8. PMID 5203 .
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