폴러2L
POLR2L
DNA 유도 RNA 중합효소 I, II, III 서브유닛 RPABC5는 사람에서 POLR2L [5]유전자에 의해 암호화되는 단백질이다.
기능.
이 유전자는 진핵생물에서 메신저 RNA를 합성하는 역할을 하는 중합효소인 RNA 중합효소 II의 서브유닛을 암호화합니다.이 유전자의 산물은 비정형 아연 결합 도메인의 특징인 4개의 보존된 시스테인을 포함한다.효모에 대한 그것의 대항체와 마찬가지로, 이 서브유닛은 다른 두 개의 DNA 지향 RNA [6]중합효소에 의해 공유될 수 있다.
상호 작용
POLR2L은 POLR2C,[7] POLR2A,[7] POLR2B[7] 및 POLR2E와 [7]상호작용하는 것으로 나타났습니다.
레퍼런스
- ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000177700 - 앙상블, 2017년 5월
- ^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000038489 - 앙상블, 2017년 5월
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Acker J, Murroni O, Mattei MG, Kedinger C, Vigneron M (September 1996). "The gene (POLR2L) encoding the hRPB7.6 subunit of human RNA polymerase". Genomics. 32 (1): 86–90. doi:10.1006/geno.1996.0079. PMID 8786124.
- ^ "Entrez Gene: POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa".
- ^ a b c d Acker J, de Graaff M, Cheynel I, Khazak V, Kedinger C, Vigneron M (July 1997). "Interactions between the human RNA polymerase II subunits". J. Biol. Chem. 272 (27): 16815–21. doi:10.1074/jbc.272.27.16815. PMID 9201987.
추가 정보
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