엑소시스트 복합성분 7은 EXOC7 [5] [6] 단백질 이다.그것은 이전에 Exo70으로 알려져 있었다.
그것 은 세포외 복합체의 서브유닛을 형성한다.사카로미세스 세레비시아 세포외 단백질은 [7] 포함 한 몇몇 다른 진핵생물에서 관찰되었습니다.S. cerevisiae 에서, 엑소포시스 복합체 는 엑소포시스 후기에 관여하며,[7] 효모 의 엑소포시스 주요 부위인 싹 끝에 국소화된다.Rho3 [8] GTPase 와 상호작용 합니다. 이 상호작용은 세포 극성에 있어서 Rho3의 알려진 세 가지 기능 중 하나를 매개합니다: 소포 도킹과 혈장막 과의 융합 (다른 두 가지 기능 은 액틴 극성 의 조절 과 모세포에서 [9] 소포 의 운반). 인간에서, 이 단백질과 세포외 복합체의 기능은 덜 잘 특징지어진다: 이 단백질은 여러 조직 에서 발현되고 세포외 [10]
상호 작용 EXOC7은 EXOC4 [11] [12] RHOQ 와 [12] 것 으로 나타났습니다.
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PDB 갤러리
2pft : 마우스 엑소70의 크리스털 구조가 포유동물 엑소시스트의 독특한 특징을 드러낸다.
