CYP6M2

CYP6M2
시토크롬 P450 6m2
식별자
유기체아노펠레스감비아
기호.Cyp6m2
엔트레즈5668319
기타 데이터
EC 번호1.14.-.-

CYP6M2살충제 [1]내성 염색체 3R의 유전자 위치이다.이 유전자에 의해 코드된 효소는 피레트로이드[2]직접 대사할 수 있으며, 시토크롬 P450 계열[3] CYP6에 속합니다.

레퍼런스

  1. ^ Djouaka, RF; Bakare, AA; Coulibaly, ON; Akogbeto, MC; Ranson, H; Hemingway, J; Strode, C (13 November 2008). "Expression of the cytochrome P450s, CYP6P3 and CYP6M2 are significantly elevated in multiple pyrethroid resistant populations of Anopheles gambiae s.s. from Southern Benin and Nigeria". BMC Genomics. 9: 538. doi:10.1186/1471-2164-9-538. PMC 2588609. PMID 19014539.
  2. ^ Ismail HM, O'Neill PM, Hong DW, Finn RD, Henderson CJ, Wright AT, et al. (December 2013). "Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions". Proceedings of the National Academy of Sciences of the United States of America. 110 (49): 19766–71. Bibcode:2013PNAS..11019766I. doi:10.1073/pnas.1320185110. PMC 3856776. PMID 24248381.
  3. ^ Wagah, MG; Korlević, P; Clarkson, C; Miles, A; Anopheles gambiae 1000 Genomes, Consortium.; Lawniczak, MKN; Makunin, A (25 May 2021). "Genetic variation at the Cyp6m2 putative insecticide resistance locus in Anopheles gambiae and Anopheles coluzzii". Malaria Journal. 20 (1): 234. doi:10.1186/s12936-021-03757-4. PMC 8146665. PMID 34034756.

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