케라틴 13

KRT13
식별자
별칭	KRT13, CK13, K13, WSN2, 케라틴 13
외부 ID	OMIM: 148065 MGI: 101925 HomoloGene: 40740 GeneCard: KRT13
유전자 위치(인간)
쳇.	17번 염색체(인간)
끝	41,505,705bp
유전자 위치(마우스)
쳇.	11번 염색체(쥐)
끝	100,195,566 bp
RNA 표현 패턴
	표현된 상단
	식도; ; 질질 끌다; ; 구강; ; 잇몸; ; 자궁경부 상피;
	추가 참조 표현식 데이터
	n/a
유전자 온톨로지
분자함수	구조 분자 활성; GO:0001948 단백질 결합;
셀룰러 컴포넌트	중간 필라멘트 사이토스켈레톤; 각질 필라멘트; 세포외 외성체; 중간 필라멘트; 핵의; 시토솔;
생물학적 과정	레티노산에 대한 세포 반응; 방사능에 대한 반응; 사이토스켈레톤 조직; 혀모형생식; 각질화; 옥수수화;
	출처:아미고 / 퀵고
직교체
	3860
	16663
	ENSG00000171401
	ENSMUSG00000044041
	P13646
	P08730
	NM_153490; NM_002274
	NM_010662; NM_0013949
	NP_002265; NP_705694
	NP_001300878; NP_034792
	위키다타
인간 보기/편집	마우스 보기/편집

케라틴 13(또는 사이토케라틴 13)은 인간에서 KRT13 유전자에 의해 암호화된 단백질이다.^[5]^[6]

케라틴 13은 I형 사이토케라틴으로, 케라틴 4와 짝을 이루며, 비옥연성 성층 상피아의 초프라바살 층에서 발견된다. 이 단백질과 케라틴 4를 부호화하는 유전자의 돌연변이는 자가 우성 질환인 화이트 스펀지 네부스와 관련이 있다.^[7]

참조

^ ^a ^b ^c GRCh38: 앙상블 릴리스 89: ENSG00000171401 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리스 89: ENSMUSG000044041 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Romano V, Raimondi E, Bosco P, Feo S, Di Pietro C, Leube RE, Troyanovsky SM, Ceratto N (October 1992). "Chromosomal mapping of human cytokeratin 13 gene (KRT13)". Genomics. 14 (2): 495–7. doi:10.1016/S0888-7543(05)80250-2. PMID 1385306.
^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
^ Richard G, De Laurenzi V, Didona B, Bale SJ, Compton JG (December 1995). "Keratin 13 point mutation underlies the hereditary mucosal epithelial disorder white sponge nevus". Nat. Genet. 11 (4): 453–5. doi:10.1038/ng1295-453. PMID 7493031. S2CID 22769768.

추가 읽기

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Shibuya Y, Zhang J, Yokoo S, et al. (2003). "Constitutional mutation of keratin 13 gene in familial white sponge nevus". Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 96 (5): 561–5. doi:10.1016/s1079-2104(03)00372-x. PMID 14600690.
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Raspollini MR, Fambrini M, Marchionni M, et al. (2007). "In situ adenocarcinoma and squamous carcinoma of uterine cervix. Pathological and immunohistochemical analysis with cytokeratin 13". Eur. J. Obstet. Gynecol. Reprod. Biol. 134 (2): 249–53. doi:10.1016/j.ejogrb.2006.07.047. PMID 16949723.
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17번 염색체의 유전자에 관한 이 기사는 단조롭다. 위키피디아를 확장하여 도울 수 있다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리스 89: ENSG00000171401 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리스 89: ENSMUSG000044041 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1385306-5] Romano V, Raimondi E, Bosco P, Feo S, Di Pietro C, Leube RE, Troyanovsky SM, Ceratto N (October 1992). "Chromosomal mapping of human cytokeratin 13 gene (KRT13)". Genomics. 14 (2): 495–7. doi:10.1016/S0888-7543(05)80250-2. PMID 1385306.

[pmid16831889-6] Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.

[pmid7493031-7] Richard G, De Laurenzi V, Didona B, Bale SJ, Compton JG (December 1995). "Keratin 13 point mutation underlies the hereditary mucosal epithelial disorder white sponge nevus". Nat. Genet. 11 (4): 453–5. doi:10.1038/ng1295-453. PMID 7493031. S2CID 22769768.

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