피트라제핀
Pitrazepin | |
| 임상자료 | |
|---|---|
| 임신 범주 |
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| 경로: 행정 | ? |
| ATC 코드 |
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| 법적현황 | |
| 법적현황 |
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| 식별자 | |
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| CAS 번호 | |
| 펍켐 CID | |
| 켐스파이더 | |
| 유니 | |
| CompTox 대시보드 (EPA) | |
| 화학 및 물리적 데이터 | |
| 공식 | C19H19N5 |
| 어금질량 | 317.396 g·190−1 |
| 3D 모델(JSmol) | |
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Pitrazepin은 경쟁적인A GABA와 글리신 수용체 길항제다.[1][2][3] 그것은 과학 연구에서 곤충과 달팽이 신경계를 연구하는 데 사용되어 왔다.[4][5][6][7][8][9]
참고 항목
참조
- ^ Gähwiler BH, Maurer R, Wüthrich HJ (April 1984). "Pitrazepin, a novel GABAA antagonist". Neuroscience Letters. 45 (3): 311–6. doi:10.1016/0304-3940(84)90244-1. PMID 6328380. S2CID 45153546.
- ^ Braestrup C, Nielsen M (November 1985). "Interaction of pitrazepin with the GABA/benzodiazepine receptor complex and with glycine receptors". European Journal of Pharmacology. 118 (1–2): 115–21. doi:10.1016/0014-2999(85)90669-7. PMID 3002806.
- ^ Curtis DR, Gynther BD (November 1986). "Pitrazepin: a central glycine and GABA antagonist". European Journal of Pharmacology. 131 (2–3): 311–3. doi:10.1016/0014-2999(86)90590-X. PMID 3816960.
- ^ Anthony NM, Harrison JB, Sattelle DB (1993). "GABA receptor molecules of insects". Exs. 63: 172–209. doi:10.1007/978-3-0348-7265-2_8. ISBN 978-3-0348-7267-6. PMID 7678525.
- ^ Sattelle DB, Pinnock RD, Wafford KA, David JA (January 1988). "GABA receptors on the cell-body membrane of an identified insect motor neuron". Proceedings of the Royal Society B. 232 (1269): 443–56. Bibcode:1988RSPSB.232..443S. doi:10.1098/rspb.1988.0006. PMID 2451252. S2CID 40290279.
- ^ Murphy VF, Wann KT (November 1988). "The action of GABA receptor agonists and antagonists on muscle membrane conductance in Schistocerca gregaria". British Journal of Pharmacology. 95 (3): 713–22. doi:10.1111/j.1476-5381.1988.tb11697.x. PMC 1854212. PMID 2850061.
- ^ Zhang W, Han XY, Wong SM, Takeuchi H (January 1997). "Pharmacologic characteristics of excitatory gamma-amino-butyric acid (GABA) receptors in a snail neuron". General Pharmacology. 28 (1): 45–53. doi:10.1016/S0306-3623(96)00152-8. PMID 9112076.
- ^ Kim KH, Takeuchi H (June 1990). "Pharmacological characteristics of two different types of inhibitory GABA receptors on Achatina fulica neurones". European Journal of Pharmacology. 182 (1): 49–62. doi:10.1016/0014-2999(90)90492-O. PMID 2169426.
- ^ Takeuchi H (September 1992). "Sensitivities of Achatina giant neurones to putative amino acid neurotransmitters". Comparative Biochemistry and Physiology C. 103 (1): 1–12. doi:10.1016/0742-8413(92)90219-w. PMID 1360362.
