미각수용체 2형 부재 50 은 TAS2R50 [3] [4] [5] [6] 단백질 이다.
기능. TAS2R50은 대형 TAS2R 수용체 패밀리에 속합니다. TAS2R은 미각수용체 세포 표면에서 발현되며, G단백질 결합 제2 [4] 「TAS2R10 」[6]
「 」를 참조해 주세요. 레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000212126 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet . 32 (3): 397–401. doi :10.1038/ng1014 . PMID 12379855 . S2CID 20426192 . ^ a b Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (Feb 2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet Genome Res . 98 (1): 45–53. doi :10.1159/000068546 . PMID 12584440 . S2CID 1542970 . ^ Shiffman D, Ellis SG, Rowland CM, Malloy MJ, Luke MM, Iakoubova OA, Pullinger CR, Cassano J, Aouizerat BE, Fenwick RG, Reitz RE, Catanese JJ, Leong DU, Zellner C, Sninsky JJ, Topol EJ, Devlin JJ, Kane JP (Sep 2005). "Identification of Four Gene Variants Associated with Myocardial Infarction" . Am J Hum Genet . 77 (4): 596–605. doi :10.1086/491674 . PMC 1275608 PMID 16175505 . ^ a b "Entrez Gene: TAS2R50 taste receptor, type 2, member 50" . 추가 정보 Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction" . J. Biol. Chem . 277 (1): 1–4. doi :10.1074/jbc.R100054200 PMID 11696554 . Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol . 12 (4): 366–71. doi :10.1016/S0959-4388(02)00345-8 . PMID 12139982 . S2CID 37807140 . Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways" . Cell . 112 (3): 293–301. doi :10.1016/S0092-8674(03)00071-0 PMID 12581520 . S2CID 718601 . Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes" . Mol. Biol. Evol . 22 (3): 432–6. doi :10.1093/molbev/msi027 PMID 15496549 . Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-Specific Loss of Function of Bitter Taste Receptor Genes in Humans and Nonhuman Primates" . Genetics . 170 (1): 313–26. doi :10.1534/genetics.104.037523 . PMC 1449719 PMID 15744053 . 이 기사에는 미국 국립 의학 도서관 (미국 국립 의학 도서관 )의 공공 도메인 텍스트가 포함되어 있습니다.
