나트륨결합중성아미노산수송체2 Sodium-coupled neutral amino acid transporter 2
나트륨 결합 중성아미노산 트랜스포터 2는 SLC38A2 [5] [6] [7] 유전자 에 의해 인체 내에서 암호화되는 단백질 이다.
「 」를 참조해 주세요. 레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000134294 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000022462 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Sugawara M, Nakanishi T, Fei YJ, Huang W, Ganapathy ME, Leibach FH, Ganapathy V (Jul 2000). "Cloning of an amino acid transporter with functional characteristics and tissue expression pattern identical to that of system A" . J Biol Chem . 275 (22): 16473–7. doi :10.1074/jbc.C000205200 PMID 10747860 . ^ Zhang Z, Grewer C (Mar 2007). "The sodium-coupled neutral amino acid transporter SNAT2 mediates an anion leak conductance that is differentially inhibited by transported substrates" . Biophys J . 92 (7): 2621–32. Bibcode :2007BpJ....92.2621Z . doi :10.1529/biophysj.106.100776 . PMC 1864845 PMID 17237199 . ^ "Entrez Gene: SLC38A2 solute carrier family 38, member 2" .
추가 정보 Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 7 (1): 65–73. doi :10.1093/dnares/7.1.65 PMID 10718198 . Hatanaka T, Huang W, Wang H, et al. (2000). "Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A." Biochim. Biophys. Acta . 1467 (1): 1–6. doi :10.1016/S0005-2736(00)00252-2 PMID 10930503 . Freeman TL, Thiele GM, Tuma DJ, et al. (2002). "ATA2-mediated amino acid uptake following partial hepatectomy is regulated by redistribution to the plasma membrane" . Arch. Biochem. Biophys . 400 (2): 215–22. doi :10.1016/S0003-9861(02)00006-1 . PMID 12054432 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Palii SS, Chen H, Kilberg MS (2004). "Transcriptional control of the human sodium-coupled neutral amino acid transporter system A gene by amino acid availability is mediated by an intronic element" . J. Biol. Chem . 279 (5): 3463–71. doi :10.1074/jbc.M310483200 PMID 14623874 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Franchi-Gazzola R, Gaccioli F, Bevilacqua E, et al. (2005). "The synthesis of SNAT2 transporters is required for the hypertonic stimulation of system A transport activity" . Biochim. Biophys. Acta . 1667 (2): 157–66. doi :10.1016/j.bbamem.2004.09.012 PMID 15581851 . Bevilacqua E, Bussolati O, Dall'Asta V, et al. (2005). "SNAT2 silencing prevents the osmotic induction of transport system A and hinders cell recovery from hypertonic stress" . FEBS Lett . 579 (16): 3376–80. doi :10.1016/j.febslet.2005.05.002 PMID 15922329 . S2CID 30690140 . Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules" . Mol. Cell. Proteomics . 4 (9): 1240–50. doi :10.1074/mcp.M500089-MCP200 PMID 15951569 . Novak D, Quiggle F, Haafiz A (2006). "Impact of forskolin and amino acid depletion upon System A activity and SNAT expression in BeWo cells". Biochimie . 88 (1): 39–44. doi :10.1016/j.biochi.2005.07.002 . PMID 16125834 . Palii SS, Thiaville MM, Pan YX, et al. (2006). "Characterization of the amino acid response element within the human sodium-coupled neutral amino acid transporter 2 (SNAT2) System A transporter gene" . Biochem. J . 395 (3): 517–27. doi :10.1042/BJ20051867 . PMC 1462688 PMID 16445384 . Melone M, Varoqui H, Erickson JD, Conti F (2006). "Localization of the Na(+)-coupled neutral amino acid transporter 2 in the cerebral cortex". Neuroscience . 140 (1): 281–92. doi :10.1016/j.neuroscience.2006.02.042 . PMID 16616430 . S2CID 10542427 . Gaccioli F, Huang CC, Wang C, et al. (2006). "Amino acid starvation induces the SNAT2 neutral amino acid transporter by a mechanism that involves eukaryotic initiation factor 2alpha phosphorylation and cap-independent translation" . J. Biol. Chem . 281 (26): 17929–40. doi :10.1074/jbc.M600341200 PMID 16621798 . Jones HN, Ashworth CJ, Page KR, McArdle HJ (2006). "Cortisol stimulates system A amino acid transport and SNAT2 expression in a human placental cell line (BeWo)". Am. J. Physiol. Endocrinol. Metab . 291 (3): E596–603. doi :10.1152/ajpendo.00359.2005 . PMID 16621896 . S2CID 11068094 .
그룹별
SLC1 ~ 10
(1): (2): (3): (4): (5): (6): (7): (8): (9): (10):
SLC11–20
(11): (12): (13): (14): (15): (16): (17): (18): (19): (20):
SLC21~30
(21): (22): (23): (24): (25): (26): (27): (28): (29): (30):
SLC31~40
(31): (32): (33): (34): (35): (36): (37): (38): (39): (40):
SLC41~48
(41): (42): (43): (44): (45): (46): (47): (48):
