호모 사피엔스 종의 단백질 코드 유전자
KLF7 로도 알려진 크루펠 유사 인자 7(유비쿼터스) 은 인간에서 KLF7 [5] [6] 유전자에 의해 암호화되는 단백질 이다.
이 단백질은 Kruppel 유사 전사 [7] 인자의 일원입니다.
레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000118263 - 앙상블 , 2017년 5월 ^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000025959 - 앙상블 , 2017년 5월 ^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Entrez Gene: KLF7 Kruppel-like factor 7 (ubiquitous)" . ^ Matsumoto N, Laub F, Aldabe R, Zhang W, Ramirez F, Yoshida T, Terada M (October 1998). "Cloning the cDNA for a new human zinc finger protein defines a group of closely related Krüppel-like transcription factors" . The Journal of Biological Chemistry . 273 (43): 28229–37. doi :10.1074/jbc.273.43.28229 . PMID 9774444 . ^ Bieker JJ (September 2001). "Krüppel-like factors: three fingers in many pies" . The Journal of Biological Chemistry . 276 (37): 34355–8. doi :10.1074/jbc.R100043200 . PMID 11443140 . 추가 정보 Cho SY, Park PJ, Shin HJ, et al. (2007). "(-)-Catechin suppresses expression of Kruppel-like factor 7 and increases expression and secretion of adiponectin protein in 3T3-L1 cells". Am. J. Physiol. Endocrinol. Metab . 292 (4): E1166–72. doi :10.1152/ajpendo.00436.2006 . PMID 17164435 . Kawamura Y, Tanaka Y, Kawamori R, Maeda S (2006). "Overexpression of Kruppel-like factor 7 regulates adipocytokine gene expressions in human adipocytes and inhibits glucose-induced insulin secretion in pancreatic beta-cell line" . Mol. Endocrinol . 20 (4): 844–56. doi :10.1210/me.2005-0138 . PMID 16339272 . Kanazawa A, Kawamura Y, Sekine A, et al. (2005). "Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes" . Diabetologia . 48 (7): 1315–22. doi :10.1007/s00125-005-1797-0 . PMID 15937668 . Smaldone S, Laub F, Else C, et al. (2004). "Identification of MoKA, a novel F-box protein that modulates Krüppel-like transcription factor 7 activity" . Mol. Cell. Biol . 24 (3): 1058–69. doi :10.1128/MCB.24.3.1058-1069.2004 . PMC 321422 . PMID 14729953 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 . PMID 14702039 . Suzuki S, Chuang LF, Doi RH, Chuang RY (2004). "Identification of opioid-regulated genes in human lymphocytic cells by differential display: upregulation of Krüppel-like factor 7 by morphine". Exp. Cell Res . 291 (2): 340–51. doi :10.1016/S0014-4827(03)00408-7 . PMID 14644156 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 . Matsumoto N, Laub F, Aldabe R, et al. (1998). "Cloning the cDNA for a new human zinc finger protein defines a group of closely related Krüppel-like transcription factors" . J. Biol. Chem . 273 (43): 28229–37. doi :10.1074/jbc.273.43.28229 . PMID 9774444 .
외부 링크
(1) 기본 도메인
(1.1 ) 베이직 류신 지퍼(bZIP )(1.2) 기본나선-루프-나선 (bHLH )
그룹 A 그룹 B 그룹 C bHLH-PAS 그룹 D 그룹 E 그룹 F bHLH-COE
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) 기본나선경간나선(bHSH)
(2.1) 핵수용체 (CYS4 )
서브패밀리 1 서브패밀리 2 서브 패밀리 3 서브패밀리 4 서브패밀리 5 서브패밀리 6 서브패밀리 0
(2.2) 기타 CY4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) 교대 조성 (2.6) WRKY